B Vitamins are nature’s “feel-good” nutrients, promoting energy, stamina, mental clarity and improved mood. Sublingual B-12, B-6 & Folic Acid tablets are designed to dissolve under the tongue to speed B Vitamins directly to the bloodstream where they go to work – without the need for expensive, often painful, B-12 injections.

Unlike caffeine and other artificial stimulants, B vitamins don’t give you that artificial jolt of energy, followed by an inevitable letdown. Your body uses B vitamins the way nature intended – to give you sustained stamina and mental clarity throughout the day, every day.

Laboratory tests show a sublingual delivery system raised blood levels of vitamin B-12 by 90% One great-tasting tablet melts quickly under your tongue and is absorbed directly into the bloodstream – providing you over 100% of the RDI for B-12, B-6 and Folic Acid Boosts energy levels, restores mental clarity and supports emotional balance 

Vegetarians or individuals consuming a primarily plant-based diet may be at higher risk of Vitamin B12 deficiency since its best sources are animal products. In short, all the critical roles that Vitamin B12 plays in your body, combined with its difficult absorption and availability prima-rily from animal products compels a careful review of your diet to determine whether you are getting adequate levels.
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These statements have not been evaluated by the FDA. 
This product is not intended to diagnose, treat, cure, or prevent any diseases.

More Interesting Information about B12:
This information was taken from a fact sheet developed by the Clinical Nutrition Service, Warren Grant Magnuson Clinical Center, National Institutes of Health (NIH), Bethesda, MD, in conjunction with the Office of Dietary Supplements (ODS) in the Office of the Director of NIH.

Who may need a vitamin B12 supplement?

Individuals with pernicious anemia
Pernicious anemia is a form of anemia that occurs when there is an absence of intrinsic factor, a substance normally present in the stomach. Vitamin B12 binds with intrinsic factor before it is absorbed and used by your body. An absence of intrinsic factor prevents normal absorption of B12 and results in pernicious anemia.

Individuals with gastrointestinal disorders
Individuals with stomach and small intestinal disorders may not absorb enough vitamin B12 from food to maintain healthy body stores. Sprue and celiac disease are intestinal disorders caused by intolerance to protein in wheat and wheat products. Regional enteritis, localized inflammation of the stomach or small intestine, also results in generalized malabsorption of vitamin B12. Excess bacteria in the stomach and small intestine also can decrease vitamin B12 absorption.

Surgical procedures of the gastrointestinal tract such as surgery to remove all or part of the stomach often result in a loss of cells that secrete stomach acid and intrinsic factor. Surgical removal of the distal ileum, a section of the intestines, also can result in the inability to absorb B12. Anyone who has had either of these surgeries usually requires lifelong supplemental B12 to prevent a deficiency.

Older Adults
Vitamin B12 must be separated from protein in food before it can bind with intrinsic factor and be absorbed by your body. Bacterial overgrowth in the stomach and/or atrophic gastritis, an inflammation of the stomach, contribute to vitamin B12 deficiency in adults by limiting secretions of stomach acid needed to separate vitamin B12 from protein in food. 10 to 30 percent of older people may be unable to absorb vitamin B12 in food.

Vegetarians
Vegetarians who do not eat meats, fish, eggs, milk or milk products, or B12 fortified foods consume no vitamin B12 and are at high risk of developing a deficiency of vitamin B12. When adults adopt a vegetarian diet, deficiency symptoms can be slow to appear because it usually takes years to deplete normal body stores of B12.  However, severe symptoms of B12 deficiency, most often featuring poor neurological development, can show up quickly in children and breast-fed infants of women who follow a strict vegetarian diet.

What is the relationship between vitamin B12, homocysteine, and heart disease?
A deficiency of vitamin B12, folate, or vitamin B6 may increase your blood level of homocysteine, an amino acid normally found in your blood. There is evidence that an elevated blood level of homocysteine is an independent risk factor for heart disease and stroke. The evidence suggests that high levels of homocysteine may damage coronary arteries or make it easier for blood clotting cells called platelets to clump together and form a clot.
This information was taken from a fact sheet developed by the Clinical Nutrition Service, Warren Grant Magnuson Clinical Center, National Institutes of Health (NIH), Bethesda, MD, in conjunction with the Office of Dietary Supplements (ODS) in the Office of the Director of NIH.

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B-12, B-6 and Folic Acid benefits:

Vitamin B12, or cobalamin, was isolated form a liver extract in 1948 and identified as the nutritional factor in liver that prevented pernicious anemia, a deadly type of anemia characterized by large, immature red blood cells. Vitamin B12 is a bright red crystalline compound because of its high content of cobalt. Vitamin B12 works with folic acid in many body processes, including the synthesis of DNA, red blood cells, and the insulation sheath (the myelin sheath) that surrounds nerve cells and speeds the conduction of the signals along nerve cells. In order to absorb the small amounts of vitamin B12 found in food, the stomach secretes intrinsic factor, a special digestive secretion that increases the absorption of vitamin B12 in the small intestine.

Vitamin B12 supplementation could be appropriate in many conditions, including AIDS, impaired mental function in the elderly, asthma and sulfite sensitivity, depression, diabetic neuropathy, low sperm counts, multiple sclerosis, and tinnitis.

Deficiency Signs and Symptoms

Unlike other water-soluble nutrients, vitamin B12 is stored in the liver, kidney, and other body tissues. As a result, signs and symptoms of vitamin B12 deficiency may not show themselves until 5 to 6 years of poor dietary intake. The classic deficiency symptom of vitamin B12 deficiency is pernicious anemia. However, a deficiency of vitamin B12 actually affects the brain and nervous system first.

A vitamin B12 deficiency results in impaired nerve function, which can cause numbness, pins-and-needles sensations, or a burning feeling. It can also cause impaired mental function that in the elderly mimics Alzheimer’s disease. Vitamin B12 deficiency is thought to be quite common in the elderly and is a major cause of depression in this age group.

In addition to anemia and nervous system symptoms, a vitamin B12 deficiency can also result in a smooth, beefy red tongue and diarrhea. This occurs because rapidly reproducing cells such as those that line the mouth and entire gastrointestinal tract cannot replicate without vitamin B12.

Several investigators have found the level of vitamin B12 declines with age and that vitamin B12 deficiency is found in 3 to 42 percent of persons aged 65 and over. 

Researchers recently studied 100 consecutive geriatric outpatients who were seen in office-based settings for various acute and chronic medical illnesses; none of these outpatients presented symptoms of vitamin B12 deficiency-related diseases like pernicious anemia. In this group, 11 patients had serum cobalamin levels at 148 pmol/L (picomole per liter) or below, 30 patients had levels between 148 and 295 pmol/L, and 59 patients had levels above 296 pmol/L. After the initial cobalamin determination, the subjects were followed for up to 3 years. The patients with cobalamin levels below 148 pmol/L were treated and were not included in the analysis of declining cobalamin levels. The average annual serum cobalamin level decline was 18 pmol/L for patients who had higher initial serum cobalamin levels (actual range, from 224 to 292 pmol/L. For patients with lower initial cobalamin levels, the average annual serum cobalamin decline was much higher at 28 pmol/L.

These results indicate that in the elderly the following screen tests for vitamin B12 have a high cost-to-benefit ratio.

    * Level of vitamin B12 in the blood (serum cobalamin) 
    * Level of homocysteine

Correction of an underlying vitamin B12 deficiency improves mental function and quality of life in these patients quite significantly.

Vitamin B6, also known as pyridoxine is part of the B group vitamins and is water-soluble and is required for both mental and physical health.

Vitamin B6 - pyridoxine - has been shown effective for the balancing of hormonal changes in women as well as assisting the immune system and the growth of new cells. It is also used in the processing and metabolism of proteins, fats and carbohydrates, while assisting with controlling mood as well as behavior. Pyridoxine might also be of benefit for children with learning difficulties, as well as assisting in the prevention of dandruff, eczema and psoriasis.

It assists in the balancing of sodium and potassium as well as promotes red blood cell production.  It is further involved in the nucleic acids RNA as well as DNA. It is further linked to cancer immunity and fights the formation of the toxic chemical homocysteine, which is detrimental to the heart muscle.

Women in particular may suffer from pre-menstrual fluid retention, severe period pains, emotional PMS symptoms, premenstrual acne and nausea in early pregnancy. Mood swings, depression, as well as loss of sexual drive is sometimes noted when pyridoxine is in short supply and the person is on hormone replacement therapy or on birth control pills.

Deficiency of vitamin B6

Irritability, nervousness and insomnia as well as general weakness, skin changes such as dermatitis and acne as well asthma and allergies might develop when pyridoxine is in short supply. Symptoms may include nails that are ridged, an inflamed tongue as well as changes to your bones - which can include osteoporosis and arthritis. Kidney stones may also appear.

Vitamin B6 is needed by the body to manufacture its own B3 vitamin. 

Should  you be taking antidepressants, contraceptive pills or be on hormone replacement therapy you may need more of this vitamin. As this vitamin is readily lost in the urine, it must be taken regularly to ensure an adequate amount in the body. 

Anybody on a very high protein diet, using alcohol, or allergic to MSG (mono sodium glutamate) and/or tartrazine may also consider increasing their vitamin B6 intake. 

Folic acid, also known as Vitamin B9, is also referred to as folacin or folate and its chemical name is pteroylglutamic acid.

Vitamin B9 - folic acid - is required for

Folic acid is required for DNA synthesis and cell growth and is important for red blood cell formation, energy production as well as the forming of amino acids. Folic acid is essential for creating heme, the iron containing substance in hemoglobin, crucial for oxygen transport. 

It is important for healthy cell division and replication, since its involvement as coenzyme for RNA and DNA synthesis. It is also required for protein metabolism and in treating folic acid anemia. Folic acid also assists in digestion, and the nervous system, and works at improving mental as well as emotional health. This nutrient may be effective in treating depression and anxiety.

Shortage of folic acid may be indicated with diarrhea, heartburn and constipation.

Folic acid is very important in the development of the nervous system of a developing fetus.

Deficiency of Folic Acid -vitamin B9

A deficiency of folic acid on an unborn baby may increase the risk of the baby being born with spina bifida and other serious defects of the nervous system.

When deficient of folic acid, you might suffer from fatigue, acne, a sore tongue, cracking at the corners of your mouth (same as deficiency of vitamin B2, vitamin B6 as well as iron). Long term deficiency may result in anemia and later in osteoporosis, as well as cancer of the bowel and cervix.

Best used with

Folic acid is more effective when taken with vitamin B12 and vitamin B6. Vitamin C is also good to have around folic acid.

Pregnant women are sometimes advised to take a small supplement of folic acid to help prevent spina bifida and other congenial nervous disorders, and may also assist to reduce the risk of toxemia in pregnancy, premature labor and hemorrhaging. It is also thought to enhance the production of milk after delivery.

Sufferers of psoriasis may consider taking folic acid, people under stress or anyone consuming alcohol.

Women on birth control pills or busy with hormone replacement therapy may benefit from folic acid.

Localized deficiencies of folic acid may exist for smokers, as low levels have been detected in the lungs of smokers.

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These statements have not been evaluated by the FDA.
This product is not intended to diagnose, treat, cure, or prevent any diseases.